Cabergoline

Cabergoline (also called Caber, brand name Dostinex) is a long-acting dopamine D2 receptor agonist. It lowers blood prolactin very effectively with significantly fewer side effects than older dopamine agonists like bromocriptine.

Clinically approved for hyperprolactinemia and prolactinomas. In the performance world used to counter prolactin elevations from nandrolone, trenbolone or specific 19-nor steroids.

Cabergoline activates dopamine D2 receptors in the pituitary. That inhibits prolactin release at the source. Effect starts within hours and lasts days due to the long half-life (~70 hours) - so 1-2 doses per week are enough.

High prolactin is problematic: it suppresses testosterone, causes erectile dysfunction, gynecomastia and libido loss. Cabergoline solves the problem at the root.

Oral tablet, with some food to minimize nausea.

• 1 tablet = typically 0.25mg or 0.5mg.
• With food significantly reduces nausea.
• Ideally in the evening before bed because the first hours can bring dizziness or mild fatigue.

Splitting into 2 doses per week (e.g. Wednesdays and Sundays) keeps levels more stable.

Cabergoline is not for routine PCT but for targeted use with prolactin-relevant compounds:

• Nandrolone cycles (Deca, NPP): nandrolone is 19-nor and progestin-active - classic prolactin driver.
• Trenbolone cycles: tren has a progestin profile similar to nandrolone.
• Long MK-677 use: can moderately raise prolactin.
• By symptoms: dropping libido, erectile issues, gyno hint on nandrolone/tren.

For pure testosterone cycles without 19-nor compounds cabergoline is usually not needed.

Cabergoline is clinically well validated:

• Webster et al. 1994: clear superiority over bromocriptine in hyperprolactinemia, plus better tolerability.
• Pascal-Vigneron et al. 1995: high success rate normalizing prolactin over months.

• Nausea: common in the first weeks, minimizable with food and slow titration.
• Dizziness: can occur on quick standing (orthostatic hypotension).
• Heart valves: observed at very high doses (3mg+ per day) in Parkinson's patients. Extremely unlikely in PCT context (under 1mg per week).
• Vivid dreams: some report intense dreams.

Store dry and protected from light, out of reach of children. Keep original container closed.