This information is for research and educational purposes only. No medical recommendations. Products are not approved for human use. For health questions, consult a doctor.

Lexicon

Muscle & performance

Proviron (Mesterolone)

The support compound - lowers SHBG, raises free testosterone, acts anti-estrogenic.

1 min read 1 sources Titration Updated June 2026
Class
DHT derivative (oral, NOT 17a-alkylated)
Use
Oral, 1-2x per day
Half-life
about 12 hours
WADA
banned (anabolic)

Getting started

Typical dosing (research context)

Per-day figures in mg, oral. NOT 17a-alkylated - barely liver-loading. Support compound, not a main agent.

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What is Proviron?

Proviron (Mesterolone) is an oral DHT derivative with a special role: it is not a mass-building steroid but a "support compound". It is not 17a-alkylated and therefore barely liver-loading. Clinically it was used for libido and fertility topics.

This information is for research and educational purposes only. No medical advice.

How it works

Proviron binds strongly to SHBG (sex hormone binding globulin) and lowers it - raising the fraction of free, active testosterone in the blood. It also has a weak anti-estrogenic effect and binds the androgen receptor itself. That makes it a popular add-on compound that makes other steroids "freer" and more effective and supports well-being/libido.

Use and dosing

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What the research shows

The AAS pharmacology (Kicman 2008) describes the SHBG binding and androgenic action of mesterolone. As a non-17a-alkylated DHT derivative the liver risk is low.

Side effects

  • Androgenic (DHT derivative) - hair loss in predisposed individuals, acne.
  • Very low liver load (not 17a-alkylated).
  • HPTA suppression milder than with strongly anabolic steroids, but present.
  • Barely any estrogen side effects.

Storage

Store dry and cool, protected from light. Out of reach of children.

Evidence

Sources

  1. 1 Pharmacology of anabolic steroids - comprehensive review. Kicman, Br J Pharmacol, 2008

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Proviron (Mesterolone) in the catalog

Sizes, prices and availability for research use. Straight from the lexicon to the product page.

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