HGH 191AA (Somatropin)

HGH 191AA is recombinant human growth hormone with the full sequence of 191 amino acids, identical to the body's own somatropin. The 191AA label distinguishes it from older, truncated variants.

Growth hormone is the best studied item in this corner and at the same time the most overhyped. The effects on body composition are real, the functional benefit in healthy people is far smaller than the marketing suggests.

HGH acts partly directly at GH receptors and partly indirectly: it prompts the liver to produce IGF-1, which mediates many of the anabolic and regenerative effects. GH itself also has a fat-mobilizing (lipolytic) action.

The half-life of GH in the blood is short, but the IGF-1-mediated effect lasts longer. That is why you dose low and regularly rather than rarely and high.

• The HGH vial (lyophilized powder).
• Bacteriostatic water for mixing.
• U-100 insulin syringes for injection.
• Alcohol swabs and a clean workspace.

HGH is given in IU (international units), not in mg. As a rough rule: about 1mg corresponds to roughly 3 IU. Vials are usually labeled with their IU count.

• Example: dissolving a 10 IU vial with 1ml bacteriostatic water gives 10 IU per ml.
• On a U-100 insulin syringe that is 100 units for the full 10 IU.
• 2 IU is then 20 units on the syringe, 4 IU is 40 units.

Just add the water, it does not matter if it hits the powder directly. Swirl or shake until dissolved.

Subcutaneous, with the short insulin needle into the subcutaneous fat (abdomen).

• Many dose in the morning fasted, some split into morning and pre-workout.
• Disinfect the site, pinch a skin fold, inject slowly.
• Rotate injection sites.

The classic study (Rudman, 1990) gave men over 60 growth hormone and saw a moderate increase in muscle mass, more bone density and less body fat. This study helped kick off the entire anti-aging hype.

The honest correction came later: a systematic review (Liu, 2007) summarized the studies in healthy older adults and concluded that GH changes body composition slightly but does not improve function and increases the rate of side effects. It could not be recommended as an anti-aging therapy.

• Water retention, swollen hands, joint stiffness, especially at the start and at higher doses.
• Carpal-tunnel-type complaints (pinched nerve in the wrist).
• Worsened insulin sensitivity, rising blood glucose, the central risk at higher doses.
• Rarely tingling or numbness. Much of this is dose-dependent and reverses when reducing.

• Start at 2 IU, be patient, GH works over weeks, not days.
• Keep an eye on blood glucose, especially from 4 IU upward.
• Keep expectations realistic, the data are more sober than the marketing.
• Banned in official competition.

Before mixing the powder is robust, normal room temperature (around 20 to 25 degrees) is fine, ideally kept in the dark. After mixing, keep in the fridge (2 to 8 degrees), do not freeze. It stays good there for at least 8 to 10 weeks with barely any loss of potency, in practice considerably longer. Swirl or shake to mix, both are fine.