What is VIP?
VIP (vasoactive intestinal peptide) is an endogenous messenger found in many tissues that plays an inflammation-regulating, vessel-widening role. In the scene it is often used in the context of chronic inflammation and stress topics, usually nasally.
How it works
VIP dampens inflammatory messengers and regulates the immune system. It also acts on blood vessels, airways and hormone balance. Because of the very short half-life, each dose acts only briefly.
Use (nasal or subcutaneous)
VIP is frequently used nasally but also works subcutaneously.
- Nasal: a few drops or a spray per nostril.
- Subcutaneous: a small amount with the insulin syringe, use the calculator above.
Dosing
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What the research shows
A clinical study (Prasse, 2010) showed that inhaled VIP lowered inflammatory messengers in the lungs of sarcoidosis patients and was well tolerated. That supports the immune-regulating action but comes from a specific clinical context, not broad everyday use.
Side effects
- Due to the vessel-widening action, drops in blood pressure, flush or dizziness are possible.
- Irritation of the nasal mucosa (nasal), local reactions (subcutaneous).
Storage
Before mixing the powder is robust, normal room temperature (around 20 to 25 degrees) is fine, ideally kept in the dark. After mixing, keep in the fridge (2 to 8 degrees), do not freeze. It stays good there for at least 8 to 10 weeks with barely any loss of potency, in practice considerably longer. Swirl or shake to mix, both are fine.