This information is for research and educational purposes only. No medical recommendations. Products are not approved for human use. For health questions, consult a doctor.

Lexicon

Muscle & performance

Masteron P (Drostanolone Propionate)

The cutting hardening steroid - DHT derivative with an anti-estrogenic note, short ester.

1 min read 2 sources Titration Updated June 2026
Class
DHT derivative (short propionate ester)
Use
Intramuscular, every other day
Half-life
about 1-2 days
WADA
banned (anabolic)

Getting started

Typical dosing (research context)

Per-week figures in mg, split every other day (EOD). Short ester.

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What is Masteron P?

Masteron P (Drostanolone Propionate) is a DHT derivative with a short propionate ester. It is not primarily a mass-building steroid but popular for "hardening" in the cutting phase - it gives muscle a dry, defined look at low body fat. Historically drostanolone was even used for breast cancer because it acts anti-estrogenically.

This information is for research and educational purposes only. No medical advice.

How it works

As a DHT derivative masteron does not aromatize and even has a weakly anti-estrogenic effect (it competes at aromatase). That contributes to the "dry" look. The effect is mainly visible at already low body fat - at high body fat it does little visually.

Use and dosing

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What the research shows

Drostanolone has historical clinical use as an anti-estrogenic agent in breast cancer. The general AAS pharmacology (Kicman 2008, Hartgens & Kuipers 2004) describes the DHT-derivative properties.

Side effects

  • Androgenic: as a DHT derivative - hair loss in predisposed individuals, acne.
  • Lipids: can lower HDL.
  • HPTA suppression: PCT topic.
  • Barely any estrogen side effects, since no aromatization.

Storage

Store the oil solution at room temperature, protected from light - no fridge needed. Out of reach of children.

Practice

PCT / after coming off

Anabolic substances suppress the body's own testosterone production in the research context. Anyone who comes off a cycle (rather than running it continuously) typically uses a post-cycle therapy (PCT) to restart the natural axis (HPTA).

The standard scheme in the research/literature context combines a SERM (tamoxifen and/or clomifene, alternatively enclomiphene) over roughly four weeks, optionally preceded by HCG to re-sensitise the testes before the SERM block. An aromatase inhibitor (anastrozole/exemestane) belongs more to on-cycle estrogen control than to the PCT itself.

Tip: order the PCT items together with the cycle so they are already on hand when you come off.

This information serves research and educational purposes only. Not medical advice.

Evidence

Sources

  1. 1 Pharmacology of anabolic steroids - comprehensive review. Kicman, Br J Pharmacol, 2008
  2. 2 Effects of androgenic-anabolic steroids in athletes. Hartgens & Kuipers, Sports Med, 2004

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Masteron P (Drostanolone Propionate) in the catalog

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